By Sky News US Team
Thomas Eric Duncan - the first man diagnosed with ebola in the US - has died, says the Dallas facility where he was being treated.
A release from Texas Health Presbyterian Hospital said: "It is with profound sadness and heartfelt disappointment that we must inform you of the death of Thomas Eric Duncan this morning at 7:51am.
"Mr Duncan succumbed to an insidious disease, Ebola. He fought courageously in this battle."
The statement said the hospital staff were "grieving" his death and had sent condolences to his family.
The Liberian national picked up the killer virus in Liberia before flying to Texas where he was admitted to the Dallas hospital.
US authorities are monitoring about 50 people who came into contact with him.
His family said they had visited him on Tuesday at the hospital, but declined to view him via video link because his condition was too "disturbing".
Mr Duncan's nephew, Josephus Weeks, said he and his mother had been unable to sleep after seeing Mr Duncan's face over video during a previous visit.
He was being treated with an experimental drug and had been on a breathing machine while receiving kidney dialysis.
There is no approved treatment for ebola and no vaccine against the virus.
As news of Mr Duncan's death was released, Secretary of State John Kerry was making an urgent appeal for nations to "step up" their response to the outbreak of the deadly virus.
Speaking alongside British Foreign Secretary Philip Hammond, Mr Kerry said more money, equipment and personnel are needed now.
He said it is essential for airlines to keep flying to West Africa and for borders to remain open to allow for the movement of assistance and medical staff.
The US meanwhile ordered security agents at airports and other entry ports to screen arriving travellers for signs of ebola.
People arriving from ebola-stricken countries in West Africa could begin facing mandatory screening measures as early as this weekend.
Homeland Security Deputy Secretary Alejandro Mayorkas did not provide specifics on how the screenings would be conducted.
He said agents would observe all travellers for "general signs of illness".
Customs and Border Protection agents would also distribute fact sheets to arriving travellers that contain details of what symptoms to look for and directions to call a doctor if they become sick within 21 days, Mr Mayorkas said.
According to US media reports, the measures also call for some travellers to have their temperatures taken upon arrival.
The announcement comes just days after President Barack Obama signalled the possibility of tougher screening measures.
Mr Obama has been under pressure to act in the wake of first ebola diagnosis on American soil last week.
The current ebola outbreak in West Africa is the deadliest in history, and has already killed nearly 3,500 people.
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